The CDK7-cycH-p36 complex of transcription factor IIH phosphorylates p53, enhancing its sequence-specific DNA binding activity in vitro.

Phosphorylation is believed to be one of the mechanisms by which p53 becomes activated or stabilized in response to cellular stress. Previously, p53 was shown to interact with three components of transcription factor IIH (TFIIH): excision repair cross-complementing types 2 and 3 (ERCC2 and ERCC3) an...

Celý popis

Podrobná bibliografie

Vydáno v:	Mol Cell Biol
Hlavní autoři:	Lu, H, Fisher, R P, Bailey, P, Levine, A J
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 1997
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232440/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9315650/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.10.5923
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!