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A novel transcriptional regulatory region within the core promoter of the hepatocyte growth factor gene is responsible for its inducibility by cytokines via the C/EBP family of transcription factors.

Hepatocyte growth factor (HGF) is an inducible cytokine that is essential for the normal growth and development of various tissues, such as the liver. To decipher the molecular mechanisms that regulate HGF gene induction at the transcriptional level, we carried out in vitro and in vivo studies on th...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Jiang, J G, Zarnegar, R
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232424/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9315634/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.10.5758
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