p53 Nuclear Accumulation and Bcl-2 Expression in Contiguous Adenomatous Components of Colorectal Adenocarcinomas Predict Aggressive Tumor Behavior

For subsets of colorectal adenocarcinoma (CRC) patients, nuclear accumulation of p53 (p53(nac)) and Bcl-2 expression are prognostic indicators. To understand their role in the progression of CRC we evaluated 90 CRCs and their contiguous adenomatous components (CAdCs) for immunohistochemical expressi...

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Main Authors: Shanmugam, Chandrakumar, Katkoori, Venkat R., Jhala, Nirag C., Grizzle, William E., Siegal, Gene P., Manne, Upender
Formato: Artigo
Idioma:Inglês
Publicado: Histochemical Society 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2324183/
https://ncbi.nlm.nih.gov/pubmed/18071066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/jhc.7A7362.2007
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