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Dual requirement for a newly identified phosphorylation site in p70s6k.

The activation of p70s6k is associated with multiple phosphorylations at two sets of sites. The first set, S411, S418, T421, and S424, reside within the autoinhibitory domain, and each contains a hydrophobic residue at -2 and a proline at +1. The second set of sites, T229 (in the catalytic domain) a...

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Autors principals: Moser, B A, Dennis, P B, Pullen, N, Pearson, R B, Williamson, N A, Wettenhall, R E, Kozma, S C, Thomas, G
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC232413/
https://ncbi.nlm.nih.gov/pubmed/9271440
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