Ectopic expression of cyclin D1 but not cyclin E induces anchorage-independent cell cycle progression.
Normal fibroblasts are dependent on adhesion to a substrate for cell cycle progression. Adhesion-deprived Rat1 cells arrest in the G1 phase of the cell cycle, with low cyclin E-dependent kinase activity, low levels of cyclin D1 protein, and high levels of the cyclin-dependent kinase inhibitor p27kip...
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| Published in: | Mol Cell Biol |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Taylor & Francis
1997
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232412/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9271439/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.9.5640 |
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