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Epidermal growth factor receptor levels are reduced in mice with targeted disruption of the protein kinase A catalytic subunit

BACKGROUND: Epidermal Growth Factor Receptor (EGFR) is a key target molecule in current treatment of several neoplastic diseases. Hence, in order to develop and improve current drugs targeting EGFR signalling, an accurate understanding of how this signalling pathway is regulated is required. It has...

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Hlavní autoři: Oksvold, Morten P, Funderud, Ane, Kvissel, Anne-Katrine, Skarpen, Ellen, Henanger, Heidi, Huitfeldt, Henrik S, Skålhegg, Bjørn S, Ørstavik, Sigurd
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2324083/
https://ncbi.nlm.nih.gov/pubmed/18380891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-9-16
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