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The structure of Pseudomonas P51 Cl-muconate lactonizing enzyme: Co-evolution of structure and dynamics with the dehalogenation function

Bacterial muconate lactonizing enzymes (MLEs) catalyze the conversion of cis,cis-muconate as a part of the β-ketoadipate pathway, and some MLEs are also able to dehalogenate chlorinated muconates (Cl-MLEs). The basis for the Cl-MLEs dehalogenating activity is still unclear. To further elucidate the...

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Bibliographic Details
Main Authors: Kajander, Tommi, Lehtiö, Lari, Schlömann, Michael, Goldman, Adrian
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323983/
https://ncbi.nlm.nih.gov/pubmed/12930985
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