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Unique stabilizing interactions identified in the two-stranded α-helical coiled-coil: Crystal structure of a cortexillin I/GCN4 hybrid coiled-coil peptide

We determined the 1.17 Å resolution X-ray crystal structure of a hybrid peptide based on sequences from coiled-coil regions of the proteins GCN4 and cortexillin I. The peptide forms a parallel homodimeric coiled-coil, with C(α) backbone geometry similar to GCN4 (rmsd value 0.71 Å). Three stabilizing...

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Detalhes bibliográficos
Main Authors: Lee, Darin L., Ivaninskii, Sergei, Burkhard, Peter, Hodges, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley-Blackwell 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323925/
https://ncbi.nlm.nih.gov/pubmed/12824486
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