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Withdrawal from acute morphine dependence is accompanied by increased anxiety-like behavior in the elevated plus maze
Pretreatment with a single moderate dose of morphine (e.g. 5.6-10 mg/kg) 4-24 hr prior to challenge with an opioid antagonist such as naloxone results in reliable expression of behaviors that resemble aversive or emotional consequences of withdrawal from chronic opioid exposure, including suppressio...
Gorde:
| Egile Nagusiak: | , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2008
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2323908/ https://ncbi.nlm.nih.gov/pubmed/18308382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2008.01.013 |
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