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Reducing the computational complexity of protein folding via fragment folding and assembly

Understanding, and ultimately predicting, how a 1-D protein chain reaches its native 3-D fold has been one of the most challenging problems during the last few decades. Data increasingly indicate that protein folding is a hierarchical process. Hence, the question arises as to whether we can use the...

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Autors principals: Haspel, Nurit, Tsai, Chung-Jung, Wolfson, Haim, Nussinov, Ruth
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323902/
https://ncbi.nlm.nih.gov/pubmed/12761388
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