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Reliable prediction of T-cell epitopes using neural networks with novel sequence representations

In this paper we describe an improved neural network method to predict T-cell class I epitopes. A novel input representation has been developed consisting of a combination of sparse encoding, Blosum encoding, and input derived from hidden Markov models. We demonstrate that the combination of several...

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Detalhes bibliográficos
Main Authors: Nielsen, Morten, Lundegaard, Claus, Worning, Peder, Lauemøller, Sanne Lise, Lamberth, Kasper, Buus, Søren, Brunak, Søren, Lund, Ole
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323871/
https://ncbi.nlm.nih.gov/pubmed/12717023
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