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Using nondenaturing mass spectrometry to detect fortuitous ligands in orphan nuclear receptors

Nondenaturing electrospray mass spectrometry (ESI-MS) has been used to reveal the presence of potential ligands in the ligand-binding domain (LBD) of orphan nuclear receptors. This new approach, based on supramolecular mass spectrometry, allowed the detection and identification of fortuitous ligands...

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Detalhes bibliográficos
Main Authors: Potier, Noelle, Billas, Isabelle M.L., Steinmetz, Anke, Schaeffer, Christine, van Dorsselaer, Alain, Moras, Dino, Renaud, Jean-Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323851/
https://ncbi.nlm.nih.gov/pubmed/12649431
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