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How do helix–helix interactions help determine the folds of membrane proteins? Perspectives from the study of homo-oligomeric helical bundles

The final, structure-determining step in the folding of membrane proteins involves the coalescence of preformed transmembrane helices to form the native tertiary structure. Here, we review recent studies on small peptide and protein systems that are providing quantitative data on the interactions th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: DeGrado, William F., Gratkowski, Holly, Lear, James D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323850/
https://ncbi.nlm.nih.gov/pubmed/12649422
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