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Interactions Between Stressful Environment and Gene Deletions Alleviate the Expected Average Loss of Fitness in Yeast

The conjecture that the deleterious effects of mutations are amplified by stress or interaction with one another remains unsatisfactorily tested. It is now possible to reapproach this problem systematically by using genomic collections of mutants and applying stress-inducing conditions with a well-r...

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Detalhes bibliográficos
Main Authors: Jasnos, Lukasz, Tomala, Katarzyna, Paczesniak, Dorota, Korona, Ryszard
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323800/
https://ncbi.nlm.nih.gov/pubmed/18430936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.084533
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