Core binding factor cannot synergistically activate the myeloperoxidase proximal enhancer in immature myeloid cells without c-Myb.

The myeloperoxidase (MPO) gene is transcribed specifically in immature myeloid cells and is regulated in part by a 414-bp proximal enhancer. Mutation of a core binding factor (CBF)-binding site at -288 decreased enhancer activity 30-fold in 32D cl3 myeloid cells cultured in granulocyte colony-stimul...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Britos-Bray, M, Friedman, A D
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232363/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9271390/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.9.5127
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