SORL1 variants and risk of late-onset Alzheimer's disease

A recent study reported significant association of late-onset Alzheimer's disease (LOAD) with multiple single nucleotide polymorphisms (SNPs) and haplotypes in SORL1, a neuronal sortilin-related receptor protein known to be involved in the trafficking and processing of amyloid precursor protein...

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Autores principales: Li, Yonghong, Rowland, Charles, Catanese, Joseph, Morris, John, Lovestone, Simon, O'Donovan, Michael C., Goate, Alison, Owen, Michael, Williams, Julie, Grupe, Andrew
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323581/
https://ncbi.nlm.nih.gov/pubmed/17949987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2007.09.001
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