Hepatocyte nuclear factor 1alpha gene inactivation impairs chromatin remodeling and demethylation of the phenylalanine hydroxylase gene.

Hepatocyte nuclear factor 1 alpha (HNF1alpha) is a homeoprotein that is expressed in the liver, kidney, pancreas, and digestive tract. Its inactivation in mouse resulted in decreased transcription of known target genes such as albumin and alpha1-antitrypsin. In contrast, the phenylalanine hydroxylas...

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Опубликовано в::	Mol Cell Biol
Главные авторы:	Pontoglio, M, Faust, D M, Doyen, A, Yaniv, M, Weiss, M C
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Taylor & Francis 1997
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232346/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9271373/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.9.4948
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