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Rapid short-duration hypothermia with cold saline and endovascular cooling before reperfusion reduces microvascular obstruction and myocardial infarct size

BACKGROUND: The aim of this study was to evaluate the combination of a rapid intravenous infusion of cold saline and endovascular hypothermia in a closed chest pig infarct model. METHODS: Pigs were randomized to pre-reperfusion hypothermia (n = 7), post-reperfusion hypothermia (n = 7) or normothermi...

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Detalhes bibliográficos
Main Authors: Götberg, Matthias, Olivecrona, Goran K, Engblom, Henrik, Ugander, Martin, van der Pals, Jesper, Heiberg, Einar, Arheden, Håkan, Erlinge, David
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323360/
https://ncbi.nlm.nih.gov/pubmed/18402663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2261-8-7
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