Illegitimate recombination leading to allelic loss and unbalanced translocation in p53-mutated human lymphoblastoid cells.

Allelic loss and translocation are critical mutational events in human tumorigenesis. Allelic loss, which is usually identified as loss of heterozygosity (LOH), is frequently observed at tumor suppressor loci in various kinds of human tumors. It is generally thought to result from deletion or mitoti...

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Bibliografiska uppgifter
Huvudupphovsmän: Honma, M, Zhang, L S, Hayashi, M, Takeshita, K, Nakagawa, Y, Tanaka, N, Sofuni, T
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1997
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC232329/
https://ncbi.nlm.nih.gov/pubmed/9234733
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