Inhibitors of Pathogen Intercellular Signals as Selective Anti-Infective Compounds

Long-term antibiotic use generates pan-resistant super pathogens. Anti-infective compounds that selectively disrupt virulence pathways without affecting cell viability may be used to efficiently combat infections caused by these pathogens. A candidate target pathway is quorum sensing (QS), which man...

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Detalhes bibliográficos
Main Authors: Lesic, Biliana, Lépine, François, Déziel, Eric, Zhang, Jiangwen, Zhang, Qunhao, Padfield, Katie, Castonguay, Marie-Hélène, Milot, Sylvain, Stachel, Scott, Tzika, A. Aria, Tompkins, Ronald G, Rahme, Laurence G
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323289/
https://ncbi.nlm.nih.gov/pubmed/17941706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0030126
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