A SAP30 Complex Inhibits IFN-β Expression in Rift Valley Fever Virus Infected Cells

Rift Valley fever virus (RVFV) nonstructural protein NSs acts as the major determinant of virulence by antagonizing interferon β (IFN-β) gene expression. We demonstrate here that NSs interacts with the host protein SAP30, which belongs to Sin3A/NCoR/HDACs repressor complexes and interacts with the t...

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Hauptverfasser: Le May, Nicolas, Mansuroglu, Zeyni, Léger, Psylvia, Josse, Thibaut, Blot, Guillaume, Billecocq, Agnès, Flick, Ramon, Jacob, Yves, Bonnefoy, Eliette, Bouloy, Michèle
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2008
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323286/
https://ncbi.nlm.nih.gov/pubmed/18225953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0040013
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