The amino-terminal transforming region of simian virus 40 large T and small t antigens functions as a J domain.

Simian virus 40 (SV40) encodes two proteins, large T antigen and small t antigen that contribute to virus-induced tumorigenesis. Both proteins act by targeting key cellular regulatory proteins and altering their function. Known targets of the 708-amino-acid large T antigen include the three members...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Srinivasan, A, McClellan, A J, Vartikar, J, Marks, I, Cantalupo, P, Li, Y, Whyte, P, Rundell, K, Brodsky, J L, Pipas, J M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232328/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9234732/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.8.4761
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