eIF2-dependent and eIF2-independent modes of initiation on the CSFV IRES: a common role of domain II

Specific interactions of the classical swine fever virus internal ribosomal entry site (IRES) with 40S ribosomal subunits and eukaryotic translation initiation factor (eIF)3 enable 43S preinitiation complexes containing eIF3 and eIF2–GTP–Met-tRNA(Met)(i) to bind directly to the initiation codon, yie...

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Autors principals: Pestova, Tatyana V, de Breyne, Sylvain, Pisarev, Andrey V, Abaeva, Irina S, Hellen, Christopher U T
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323255/
https://ncbi.nlm.nih.gov/pubmed/18337746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.49
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