Extensive genomic diversity and selective conservation of virulence-determinants in enterohemorrhagic Escherichia coli strains of O157 and non-O157 serotypes

BACKGROUND: Enterohemorrhagic Escherichia coli (EHEC) O157 causes severe food-borne illness in humans. The chromosome of O157 consists of 4.1 Mb backbone sequences shared by benign E. coli K-12, and 1.4 Mb O157-specific sequences encoding many virulence determinants, such as Shiga toxin genes (stx g...

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Bibliografiske detaljer
Main Authors: Ogura, Yoshitoshi, Ooka, Tadasuke, Asadulghani, Terajima, Jun, Nougayrède, Jean-Philippe, Kurokawa, Ken, Tashiro, Kousuke, Tobe, Toru, Nakayama, Keisuke, Kuhara, Satoru, Oswald, Eric, Watanabe, Haruo, Hayashi, Tetsuya
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2007
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323221/
https://ncbi.nlm.nih.gov/pubmed/17711596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-7-r138
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