Air-pollutant chemicals and oxidized lipids exhibit genome-wide synergistic effects on endothelial cells

BACKGROUND: Ambient air pollution is associated with increased cardiovascular morbidity and mortality. We have found that exposure to ambient ultrafine particulate matter, highly enriched in redox cycling organic chemicals, promotes atherosclerosis in mice. We hypothesize that these pro-oxidative ch...

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Autores principales: Gong, Ke Wei, Zhao, Wei, Li, Ning, Barajas, Berenice, Kleinman, Michael, Sioutas, Constantinos, Horvath, Steve, Lusis, Aldons J, Nel, Andre, Araujo, Jesus A
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323217/
https://ncbi.nlm.nih.gov/pubmed/17655762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-7-r149
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