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Housekeeping genes tend to show reduced upstream sequence conservation
BACKGROUND: Understanding the constraints that operate in mammalian gene promoter sequences is of key importance to understand the evolution of gene regulatory networks. The level of promoter conservation varies greatly across orthologous genes, denoting differences in the strength of the evolutiona...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2323216/ https://ncbi.nlm.nih.gov/pubmed/17626644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-7-r140 |
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