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Structure-function analysis of the Saccharomyces cerevisiae G1 cyclin Cln2.

We have generated 50 new alleles of the yeast CLN2 gene by using site-directed mutagenesis. With the recently obtained crystal structure of cyclin A as a guide, a peptide linker sequence was inserted at 13 sites within the cyclin box of Cln2 to determine if the architecture of Cln2 is similar to tha...

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Publicat a:Mol Cell Biol
Autors principals: Huang, K N, Odinsky, S A, Cross, F R
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1997
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232318/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9234722/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.8.4654
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