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Pro-protein convertases control the maturation and processing of the iron-regulatory protein, RGMc/hemojuvelin
BACKGROUND: Repulsive guidance molecule c (RGMc or hemojuvelin), a glycosylphosphatidylinositol-linked glycoprotein expressed in liver and striated muscle, plays a central role in systemic iron balance. Inactivating mutations in the RGMc gene cause juvenile hemochromatosis (JH), a rapidly progressin...
Gorde:
| Egile Nagusiak: | , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
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BioMed Central
2008
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2323002/ https://ncbi.nlm.nih.gov/pubmed/18384687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-9-9 |
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