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Interdigitated residues within a small region of VP16 interact with Oct-1, HCF, and DNA.

Upon infection, the herpes simplex virus (HSV) activator of immediate-early (IE) gene transcription VP16 forms a multiprotein-DNA complex with two cellular proteins, Oct-1 and HCF. First, VP16 associates with HCF independently of DNA, and this association stimulates subsequent association with Oct-1...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Biol
Autori principali: Lai, J S, Herr, W
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1997
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232246/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9199328/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.7.3937
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