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Specific regulation of E2F family members by cyclin-dependent kinases.

The transcription factor E2F-1 interacts stably with cyclin A via a small domain near its amino terminus and is negatively regulated by the cyclin A-dependent kinases. Thus, the activities of E2F, a family of transcription factors involved in cell proliferation, are regulated by at least two types o...

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Autors principals: Dynlacht, B D, Moberg, K, Lees, J A, Harlow, E, Zhu, L
Format: Artigo
Idioma:Inglês
Publicat: 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC232239/
https://ncbi.nlm.nih.gov/pubmed/9199321
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