Interaction between the small GTPase Ran/Gsp1p and Ntf2p is required for nuclear transport.

Bidirectional movement of proteins and RNAs across the nuclear envelope requires Ran, a Ras-like GTPase. A genetic screen of the yeast Saccharomyces cerevisiae was performed to isolate conditional alleles of GSP1, a gene that encodes a homolog of Ran. Two temperature-sensitive alleles, gsp1-1 and gs...

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Main Authors: Wong, D H, Corbett, A H, Kent, H M, Stewart, M, Silver, P A
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC232227/
https://ncbi.nlm.nih.gov/pubmed/9199309
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