Recombination signal sequence binding protein Jkappa is constitutively bound to the NF-kappaB site of the interleukin-6 promoter and acts as a negative regulatory factor.

Eitemau Tebyg

• Constitutive silencing of IFN-beta promoter is mediated by NRF (NF-kappaB-repressing factor), a nuclear inhibitor of NF-kappaB.
  gan: Nourbakhsh, M, et al.
  Cyhoeddwyd: (1999)
• Constitutive transcription of the human interleukin-6 gene by rheumatoid synoviocytes: spontaneous activation of NF-kappaB and CBF1.
  gan: Miyazawa, K., et al.
  Cyhoeddwyd: (1998)
• Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth.
  gan: Nakshatri, H, et al.
  Cyhoeddwyd: (1997)
• NF-kappaB in Lung Tumorigenesis
  gan: Cai, Zhenjian, et al.
  Cyhoeddwyd: (2011)
• Prevalence of bortezomib-resistant constitutive NF-kappaB activity in mantle cell lymphoma
  gan: Yang, David T, et al.
  Cyhoeddwyd: (2008)