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Coordinate transcription and V(D)J recombination of the kappa immunoglobulin light-chain locus: NF-kappaB-dependent and -independent pathways of activation.

To further elucidate the potential role of mitogens and cytokines in regulation of the kappa immunoglobulin light-chain locus, we have characterized the activation of transcription factor binding, kappa germ line transcription, DNase I hypersensitivity, and Vkappa-to-Jkappa recombination upon induct...

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Pubblicato in:Mol Cell Biol
Autori principali: O'Brien, D P, Oltz, E M, Van Ness, B G
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1997
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232201/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9199283/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.7.3477
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