A lesion in the DNA replication initiation factor Mcm10 induces pausing of elongation forks through chromosomal replication origins in Saccharomyces cerevisiae.

We describe a new minichromosome maintenance factor, Mcm10, and show that this essential protein is involved in the initiation of DNA replication in Saccharomyces cerevisiae. The mcm10 mutant has an autonomously replicating sequence-specific minichromosome maintenance defect and arrests at the nonpe...

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Bibliografski detalji
Glavni autori: Merchant, A M, Kawasaki, Y, Chen, Y, Lei, M, Tye, B K
Format: Artigo
Jezik:Inglês
Izdano: 1997
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC232179/
https://ncbi.nlm.nih.gov/pubmed/9154825
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