Template topology and transcription: chromatin templates relaxed by localized linearization are transcriptionally active in yeast.

To address the role of transient torsional stress in transcription, we have utilized the regulated expression of HO endonuclease in yeast to create double-strand breaks in DNA templates in vivo at preselected sites. Linearization of circular minichromosomes, either 2 kb upstream or immediately downs...

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Bibliografische gegevens

Gepubliceerd in:	Mol Cell Biol
Hoofdauteurs:	Liang, C P, Garrard, W T
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Taylor & Francis 1997
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232134/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9111354/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.5.2825
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