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Nuclear receptor corepressors activate rather than suppress basal transcription of genes that are negatively regulated by thyroid hormone.

A group of transcriptional cofactors referred to as corepressors (CoRs) were recently shown to play a central role in basal silencing of genes that contain positive triiodothyronine (T3) response elements. In a reciprocal manner, negatively regulated genes are stimulated by unliganded thyroid hormon...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Tagami, T, Madison, L D, Nagaya, T, Jameson, J L
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232114/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9111334/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.5.2642
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