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Transcriptional activation and transformation by FosB protein require phosphorylation of the carboxyl-terminal activation domain.

The transcription factor AP-1, composed of Fos-Jun dimers, mediates some aspects of the cellular response to growth factors. Transcriptional activation and neoplastic transformation by FosB, a member of the Fos family of proteins, require the presence of a potent C-terminal activation domain. Here w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Skinner, M, Qu, S, Moore, C, Wisdom, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1997
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC232086/
https://ncbi.nlm.nih.gov/pubmed/9111306
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