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Carboxyfullerenes as neuroprotective agents

Two regioisomers with C(3) or D(3) symmetry of water-soluble carboxylic acid C(60) derivatives, containing three malonic acid groups per molecule, were synthesized and found to be equipotent free radical scavengers in solution as assessed by EPR analysis. Both compounds also inhibited the excitotoxi...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Dugan, Laura L., Turetsky, Dorothy M., Du, Cheng, Lobner, Doug, Wheeler, Mark, Almli, C. Robert, Shen, Clifton K.-F., Luh, Tien-Yau, Choi, Dennis W., Lin, Tien-Sung
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1997
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23208/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9256500/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.17.9434
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