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The PRK2 kinase is a potential effector target of both Rho and Rac GTPases and regulates actin cytoskeletal organization.

The Ras-related Rho family GTPases mediate signal transduction pathways that regulate a variety of cellular processes. Like Ras, the Rho proteins (which include Rho, Rac, and CDC42) interact directly with protein kinases, which are likely to serve as downstream effector targets of the activated GTPa...

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Bibliografski detalji
Izdano u:Mol Cell Biol
Glavni autori: Vincent, S, Settleman, J
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 1997
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232074/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9121475/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.4.2247
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