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The adenovirus E1A repression domain disrupts the interaction between the TATA binding protein and the TATA box in a manner reversible by TFIIB.

The human adenovirus E1A 243 amino acid oncoprotein possesses a transcription repression function that appears to be linked with its ability to induce cell cycle progression and to inhibit cell differentiation. The molecular mechanism of E1A repression has been poorly understood. Recently, we report...

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Библиографические подробности
Главные авторы: Song, C Z, Loewenstein, P M, Toth, K, Tang, Q, Nishikawa, A, Green, M
Формат: Artigo
Язык:Inglês
Опубликовано: 1997
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC232067/
https://ncbi.nlm.nih.gov/pubmed/9121468
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