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Repression of the heat shock factor 1 transcriptional activation domain is modulated by constitutive phosphorylation.

Heat shock transcription factor 1 (HSF1) is constitutively expressed in mammalian cells and negatively regulated for DNA binding and transcriptional activity. Upon exposure to heat shock and other forms of chemical and physiological stress, these activities of HSF1 are rapidly induced. In this repor...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Kline, M P, Morimoto, R I
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1997
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232058/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9121459/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.4.2107
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