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An RNA-binding protein recognizes a mammalian selenocysteine insertion sequence element required for cotranslational incorporation of selenocysteine.

In mammalian selenoprotein mRNAs, the recognition of UGA as selenocysteine requires selenocysteine insertion sequence (SECIS) elements that are contained in a stable stem-loop structure in the 3' untranslated region (UTR). In this study, we investigated the SECIS elements and cellular proteins requi...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Lesoon, A, Mehta, A, Singh, R, Chisolm, G M, Driscoll, D M
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1997
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232044/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9121445/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.4.1977
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