Loading...

Position-dependent transcriptional regulation of the murine dihydrofolate reductase promoter by the E2F transactivation domain.

Activity of the dihydrofolate reductase (dhfr) promoter increases at the G1-S-phase boundary of the cell cycle. Mutations that abolish protein binding to an E2F element in the dhfr promoter also abolish the G1-S-phase increase in dhfr transcription, indicating that transcriptional regulation is medi...

Full description

Saved in:
Bibliographic Details
Main Authors: Fry, C J, Slansky, J E, Farnham, P J
Format: Artigo
Language:Inglês
Published: 1997
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC232043/
https://ncbi.nlm.nih.gov/pubmed/9121444
Tags: Add Tag
No Tags, Be the first to tag this record!