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Potent, protective anti-HIV immune responses generated by bimodal HIV envelope DNA plus protein vaccination

It is generally thought that an effective vaccine to prevent HIV-1 infection should elicit both strong neutralizing antibody and cytotoxic T lymphocyte responses. We recently demonstrated that potent, boostable, long-lived HIV-1 envelope (Env)-specific cytotoxic T lymphocyte responses can be elicite...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Letvin, Norman L., Montefiori, David C., Yasutomi, Yasuhiro, Perry, Helen C., Davies, Mary-Ellen, Lekutis, Christine, Alroy, Marianne, Freed, Daniel C., Lord, Carol I., Handt, Laurence K., Liu, Margaret A., Shiver, John W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1997
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23198/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9256490/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.17.9378
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