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Potent, protective anti-HIV immune responses generated by bimodal HIV envelope DNA plus protein vaccination

It is generally thought that an effective vaccine to prevent HIV-1 infection should elicit both strong neutralizing antibody and cytotoxic T lymphocyte responses. We recently demonstrated that potent, boostable, long-lived HIV-1 envelope (Env)-specific cytotoxic T lymphocyte responses can be elicite...

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Detalhes bibliográficos
Main Authors: Letvin, Norman L., Montefiori, David C., Yasutomi, Yasuhiro, Perry, Helen C., Davies, Mary-Ellen, Lekutis, Christine, Alroy, Marianne, Freed, Daniel C., Lord, Carol I., Handt, Laurence K., Liu, Margaret A., Shiver, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23198/
https://ncbi.nlm.nih.gov/pubmed/9256490
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