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A maternal diet high in n − 6 polyunsaturated fats alters mammary gland development, puberty onset, and breast cancer risk among female rat offspring

We hypothesized that feeding pregnant rats with a high-fat diet would increase both circulating 17β-estradiol (E2) levels in the dams and the risk of developing carcinogen-induced mammary tumors among their female offspring. Pregnant rats were fed isocaloric diets containing 12% or 16% (low fat) or...

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Autores principales: Hilakivi-Clarke, Leena, Clarke, Robert, Onojafe, Ighovie, Raygada, Margarita, Cho, Elizabeth, Lippman, Marc
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences of the USA 1997
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC23197/
https://ncbi.nlm.nih.gov/pubmed/9256489
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