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The nonconserved hinge region and distinct amino-terminal domains of the ROR alpha orphan nuclear receptor isoforms are required for proper DNA bending and ROR alpha-DNA interactions.

ROR alpha 1 and ROR alpha 2 are two isoforms of a novel member of the steroid-thyroid-retinoid receptor superfamily and are considered orphan receptors since their cognate ligand has yet to be identified. These putative receptors have previously been shown to bind as monomers to a DNA recognition se...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: McBroom, L D, Flock, G, Giguère, V
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231954/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7823947/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.2.796
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