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Constitutive c-myb expression in K562 cells inhibits induced erythroid differentiation but not tetradecanoyl phorbol acetate-induced megakaryocytic differentiation.

K562 cells were stably transfected with a plasmid vector constitutively expressing a full-length human c-myb gene. Parental cells possess the dual potential of inducibility of cellular differentiation along two lineages, i.e., erythroid and megakaryocytic. The resulting lineage is dependent on the i...

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Publicat a:Mol Cell Biol
Autors principals: Rosson, D, O'Brien, T G
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231948/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7823945/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.2.772
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