Distinct roles of the molecular chaperone hsp90 in modulating dioxin receptor function via the basic helix-loop-helix and PAS domains.

The intracellular dioxin receptor mediates signal transduction by dioxin and functions as a ligand-activated transcription factor. It contains a basic helix-loop-helix (bHLH) motif contiguous with a Per-Arnt-Sim (PAS) homology region. In extracts from nonstimulated cells the receptor is recovered in...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Antonsson, C, Whitelaw, M L, McGuire, J, Gustafsson, J A, Poellinger, L
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1995
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231944/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7823943/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.2.756
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