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Distinct roles of the molecular chaperone hsp90 in modulating dioxin receptor function via the basic helix-loop-helix and PAS domains.

The intracellular dioxin receptor mediates signal transduction by dioxin and functions as a ligand-activated transcription factor. It contains a basic helix-loop-helix (bHLH) motif contiguous with a Per-Arnt-Sim (PAS) homology region. In extracts from nonstimulated cells the receptor is recovered in...

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Publicado en:Mol Cell Biol
Autores principales: Antonsson, C, Whitelaw, M L, McGuire, J, Gustafsson, J A, Poellinger, L
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 1995
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231944/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7823943/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.2.756
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