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Transcriptional regulation of the mouse alpha A-crystallin gene: activation dependent on a cyclic AMP-responsive element (DE1/CRE) and a Pax-6-binding site.

Two cis-acting promoter elements (-108 to -100 and -49 to -33) of the mouse alpha A-crystallin gene, which is highly expressed in the ocular lens, were studied. Here we show that DE1 (-108 to -100; 5'TGACGGTG3'), which resembles the consensus cyclic AMP (cAMP)-responsive element sequence (CRE; 5'TGA...

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Bibliografske podrobnosti
izdano v:Mol Cell Biol
Principais autores: Cvekl, A, Kashanchi, F, Sax, C M, Brady, J N, Piatigorsky, J
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 1995
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231924/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7823934/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.2.653
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