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The C-terminal zinc finger of GATA-1 or GATA-2 is sufficient to induce megakaryocytic differentiation of an early myeloid cell line.

The GATA-1 and GATA-2 transcription factors, which each contain two homologous zinc fingers, are important hematopoietic regulators expressed within the erythroid, mast cell, and megakaryocytic lineages. Enforced expression of either factor in the primitive myeloid line 416B induces megakaryocytic d...

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Udgivet i:Mol Cell Biol
Principais autores: Visvader, J E, Crossley, M, Hill, J, Orkin, S H, Adams, J M
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231921/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7823932/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.2.634
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